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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RCL
All Species:
8.48
Human Site:
Y39
Identified Species:
26.67
UniProt:
O43598
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43598
NP_006434.1
174
19108
Y39
G
R
E
D
R
T
L
Y
E
R
I
V
S
R
L
Chimpanzee
Pan troglodytes
XP_518907
121
13295
G18
N
T
G
E
E
A
A
G
G
D
R
L
I
H
E
Rhesus Macaque
Macaca mulatta
XP_001093715
174
19061
Y39
G
R
E
D
R
T
L
Y
E
R
I
V
S
R
L
Dog
Lupus familis
XP_538931
165
17954
Y41
G
R
E
D
R
A
L
Y
G
R
I
V
S
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80VJ3
173
18959
E52
H
V
A
D
A
E
L
E
P
R
G
E
E
A
A
Rat
Rattus norvegicus
O35820
163
17762
E52
H
V
A
D
A
E
L
E
P
L
G
E
E
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B8A556
143
16168
V37
G
N
V
L
T
E
H
V
S
Y
D
S
L
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195603
127
14003
R24
G
Q
K
G
E
D
A
R
V
F
S
M
L
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
65.5
94.2
78.7
N.A.
73.5
74.1
N.A.
N.A.
N.A.
N.A.
51.1
N.A.
N.A.
N.A.
N.A.
34.4
Protein Similarity:
100
68.3
95.9
84.4
N.A.
79.8
79.8
N.A.
N.A.
N.A.
N.A.
65.5
N.A.
N.A.
N.A.
N.A.
48.8
P-Site Identity:
100
0
100
86.6
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
86.6
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
25
25
25
0
0
0
0
0
0
25
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
63
0
13
0
0
0
13
13
0
0
0
13
% D
% Glu:
0
0
38
13
25
38
0
25
25
0
0
25
25
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% F
% Gly:
63
0
13
13
0
0
0
13
25
0
25
0
0
0
0
% G
% His:
25
0
0
0
0
0
13
0
0
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
38
0
13
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
13
% K
% Leu:
0
0
0
13
0
0
63
0
0
13
0
13
25
0
38
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% P
% Gln:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
38
0
0
38
0
0
13
0
50
13
0
0
38
0
% R
% Ser:
0
0
0
0
0
0
0
0
13
0
13
13
38
13
0
% S
% Thr:
0
13
0
0
13
25
0
0
0
0
0
0
0
0
0
% T
% Val:
0
25
13
0
0
0
0
13
13
0
0
38
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
38
0
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _